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NOVEL THIENOPYRIDINES ARE POTENT ANTI-PLATELET DRUGS, INHIBITING PLATELET ACTIVATION, AGGREGATION AND SHOWING SYNERGY WITH ASPIRIN.

Naif K. Binsaleh1 Catherine A. Wigley1 Kathryn A. Whitehead1 Daniel Moreno-Martinez1 Sarah Daniels1 Sarah Jones1 Michelle van Rensburg2 Lisa I. Pilkington2 David Barker2 and Nina C. Dempsey-Hibbert1.

2017

This abstract is not available online.

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Building bridges between scientific and local knowledge in relation to flooding and pollution.

Maria Loroño-Leturiondo Simon Cook Stephen R. Hoon Paul O’Hare Sam Illingworth

2017

An initial scoping survey that we conducted found that flooding and pollution are the main environmental concerns amongst Greater Manchester citizens. Building resilient communities in the face of these environmental hazards requires raising awareness, and establishing genuine two-way dialogue between experts with scientific knowledge, and non-experts with local knowledge and real-life experiences.

Finding forms of communication that work in raising awareness and in facilitating ...

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A Unified General Framework for Opinion Dynamics

Adam Coates Dr Anthony Kleerekoper

2017

Opinion dynamics is the study of how people’s opinions may change as they interact with
others in a population. This is conventionally studied by modelling people as interacting
agents with mathematical rules governing their behaviour. The field is characterised by an
uncoordinated approach to the creation of new models and rules, with no reference to a
unified general framework. This results in a large amount of duplicated work, even as a
significant portion...

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Development of a novel drug discovery platform for human skeletal muscle wasting

Marwah Abd Al Samid

2017

Background: Muscle wasting in ageing (sarcopenia) is a significant public health concern, culminating in weakness, frailty and loss of independence. Despite several decades of research using model organisms, animals and two dimensional (2D) muscle cell cultures, there remains no cure or treatment for muscle wasting. Animal models and cells do not represent human muscle ageing and disease, while 2D models do not recapitulate the 3D structure of muscle tissue and lack the m...

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Finite Element Modelling of Auxetic Materials for Sports Applications

Todd Shepherd Heather Driscoll Keith Winwood Praburaj Venkatraman Andrew Alderson Tom Allen

2017

Auxetic materials have a negative Poisson’s ratio; they get thinner when compressed and thicker when stretched, which can lead to improved mechanical properties such as increased energy absorption and resistance to indentation. A potential application of these materials is protective sport equipment, where impact forces, and hence the risk of injury, can be reduced. Existing work shows this potential but involves time-consuming development and experimental testing of material samples. The aim ...

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