Hyperglycaemia and tubulointerstitial fibrosis in renal proximal tubular epithelial cells.
F Alsehli, N Ahmed and L Shalamanova
Centre for Biomedicine, School of Healthcare Science, Manchester Metropolitan University, Manchester, UK
Background: Renal tubulointerstitial fibrosis (TIF) is the hallmark of chronic and end-stage renal disease. Around 40% of the diabetic patients develop diabetic nephropathy which is characterised by abnormal accumulation of extrac...